Sr Scientist, Discovery Sciences and Technologies
Core
Lead mRNA-LNP discovery research and formulation optimization for therapeutic applications in Virology, Oncology, and Inflammation.
Role type
Senior Scientist, Discovery Sciences & Technologies (LNP Center of Excellence)
Builds
mRNA-LNP-based drug delivery candidates and optimized lipid formulations
Domain
Biopharmaceuticals / mRNA therapeutics / Drug Delivery Systems
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Ionizable lipid chemistry, LNP formulation design, High-throughput screening, Tangential-flow filtration (TFF), Microfluidic mixing, LC-based analysis, DoE-based screening, Scientific project leadership
Preferred skills
Targeted-LNP conjugation strategies, Formulation scale-up, Technology transfer to CMC/CDMO
Technologies
Microfluidic platforms, DLS/PDI, Zeta potential analyzers, LC-MS, TFF systems
Responsibilities
Design and optimize mRNA-LNP formulations and targeted architectures; Execute high-throughput screening campaigns for transfection efficiency and immune activation; Establish QC workflows for particle characterization; Lead scientific projects and mentor junior scientists; Build strategic collaborations with academic groups and CROs.
Seniority
Senior, hands-on IC with mentorship responsibilities