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Director, Analytical Chemistry

Cambridge, Massachusetts💼 Full-time💰 $167,000–$167,000🗓 2026-05-27 → 2026-07-31

Core

Provide scientific, strategic, and organizational leadership for discovery-stage analytical chemistry activities supporting mRNA-lipid nanoparticle (LNP) research across a diverse portfolio of nucleic acid medicines.

Role type

Director, Analytical Chemistry (Discovery & Early Development)

Builds

Analytical strategies, decision-quality packages, and scalable capabilities for mRNA-LNP therapeutics and vaccines.

Domain

Biotechnology / Pharmaceutical / mRNA-LNP therapeutics

Deliverable

production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work

Required skills

Analytical chemistry leadership, separation science (UPLC, HPLC, LC-MS, GC-MS, CE, NMR), structure elucidation, impurity profiling, method development/qualification/transfer, high-throughput methodologies, AI/ML for data analysis, cross-functional partnership, CRO/CDMO management

Preferred skills

mRNA-LNP/oligonucleotide/gene editing experience, lipid library characterization, IND-enabling program experience, design-of-experiments, cheminformatics, publication/patent record

Technologies

UPLC, HPLC, LC-MS, LC-CAD, GC-MS, CE, NMR, UV/Vis, IR, LIMS, CDS, electronic laboratory notebooks

Responsibilities

Lead and develop a high-performing team of analytical scientists; Set analytical chemistry vision and strategy for discovery-stage programs; Serve as senior analytical partner to medicinal chemistry and formulation teams; Guide fit-for-purpose analytical method development and lifecycle management; Provide technical leadership in structure elucidation and impurity identification; Oversee analytical characterization strategies for large molecules and nucleic acids; Represent analytical chemistry in cross-functional governance and external interactions.

Seniority

Director, strategic oversight & hands-on technical leadership

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