Principal Scientist, Cell Culture Development
Core
Lead upstream process development for biologics, guiding recombinant products from early development to manufacturing readiness.
Role type
Principal Scientist, Cell Culture Development
Builds
High-quality recombinant biologics products
Domain
Biologics / Recombinant protein technology
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Cell culture process development, Upstream process development, Scale-up, Experimental design, Data interpretation, Regulatory documentation, Team mentorship
Preferred skills
Mammalian cell culture (CHO systems), Media development, Metabolic modelling, Bioreactor scale-down, Technology transfer
Technologies
CHO systems, Bioreactors
Responsibilities
Provide scientific leadership in cell culture process development and scale-up; Design and execute upstream development strategies across high-throughput and mid-scale platforms; Lead experimental planning, execution, and data interpretation; Support process development from clone selection to process characterisation; Guide and mentor team members; Contribute to regulatory documentation and submissions; Collaborate on tech transfer and manufacturing readiness.
