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Associate Principal Scientist – Peptide Development Chemistry - Pharmaceutical Sciences (PS)

UK - Macclesfield💼 Full-time🗓 2026-07-17 → 2026-07-30

Core

Lead the development and manufacture of peptide-containing drug substances for early clinical-phase projects, including pure-play therapeutics and conjugates.

Role type

Associate Principal Scientist (Process Chemistry)

Builds

Investigative medicines (peptide drug substances) for clinical trials

Domain

Biopharmaceuticals / Peptide Chemistry / CMC

Deliverable

production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work

Required skills

Peptide chemistry development, Conjugation chemistry (linkers/targeting agents), Large-scale laboratory manufacturing, Process design and engineering, Regulatory knowledge for clinical supply, Strategic project leadership

Preferred skills

External partnership with CROs/CDMOs, Mentorship, Cross-functional collaboration, Publishing research

Technologies

None explicitly listed

Responsibilities

Drive development and manufacture of peptide drug substances, Provide expert challenge and strategic thinking within CMC teams, Collaborate with external partners to identify specialist capabilities, Mentor and develop colleagues, Enhance scientific reputation through external engagement

Seniority

Associate Principal, hands-on IC with strategic influence

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