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Staff Engineer, Drug Substance, MSAT

Visp, Switzerland💼 Full-time🗓 2026-06-30 → 2026-07-31

Core

Staff Engineer leading Drug Substance manufacturing operations for protein-polysaccharide conjugate vaccines at contract manufacturing organizations (CMOs), ensuring commercial readiness, process validation, and efficient GMP production.

Role type

Staff Engineer, Drug Substance Manufacturing (Bioconjugates)

Builds

Commercial-grade protein-polysaccharide conjugate Drug Substances for bacterial disease vaccines

Domain

Biopharmaceuticals / Vaccine Manufacturing / Bioconjugation

Deliverable

production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work

Required skills

protein-polysaccharide conjugation chemistry, statistical process control (DOE, CPV), GMP compliance, process troubleshooting, FMEA, technology transfer, unit operations (chromatography, TFF, centrifugation), CMO management, CAPA development

Preferred skills

vaccine manufacturing experience, drug substance equipment qualification, facility fit assessment, scale-down studies, cross-functional leadership

Technologies

DOE tools, control charts, chromatography systems, UF/DF TFF, microfluidization, depth filtration

Responsibilities

oversee CMO service providers for commercial manufacturing campaigns, execute statistical data analysis for process verification, lead manufacturing process investigations and CAPAs, drive continuous improvement in conjugation processes, support technology transfer and process validation, present technical findings to senior management and external conferences

Seniority

Senior, hands-on IC with technical leadership

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