Laboratory Scientist – Biochemistry & Assay Development (full time)
Core
Design, develop, and execute biochemical assays and screening cascades to support drug discovery programs for haematological malignancies.
Role type
Laboratory Scientist (Biochemistry & Assay Development)
Builds
Biochemical screening cascades and high-quality assay data for medicinal chemistry and biology partners.
Domain
Biopharmaceuticals / Drug Discovery / Haematological Oncology
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Enzymatic and binding assay development, enzyme kinetics (Michaelis-Menten), protein-ligand interactions, dose-response analysis, selectivity profiling, experimental troubleshooting, statistical analysis of assay results, data quality assessment
Preferred skills
Biochemical screening cascade execution, biophysical methods (TR-FRET, AlphaScreen, SPR), data scripting (Python, R), drug discovery background
Technologies
TR-FRET, AlphaScreen, AlphaLISA, FP, SPR
Responsibilities
Develop and optimize biochemical assays, execute experiments independently, build and manage screening cascades, analyze experimental data, collaborate across disciplines, ensure lab compliance and safety, mentor junior team members
Seniority
Mid-level, hands-on IC