Scientist Biologic Discovery
Core
Develop, optimize, qualify, and implement novel cell-based assays to support high-throughput screening of therapeutic antibody candidates.
Role type
Scientist, Biologic Discovery (In Vitro Pharmacology)
Builds
Custom cell-based bioassays for identifying and characterizing therapeutic antibodies
Domain
Biotechnology / Biologic Discovery
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
mammalian cell culture, transfection, ELISA, flow cytometry, fluorescence imaging, assay development, high-throughput screening, data analysis, experimental design, troubleshooting
Preferred skills
cytokine release assay, cell activation/proliferation assays, phosphorylation assays, reporter assays, ADCC assay, antibody-drug conjugate (ADC) bioassays, automated liquid handlers, multimode plate readers, imaging systems
Technologies
Envision, IncuCyte, Opera Phenix/Operetta, CytoFLEX, Bravo
Responsibilities
Design, execute, analyze, and document experiments for assay development and screening; operate laboratory equipment including flow cytometers and liquid handlers; troubleshoot complex technical issues; collaborate with cross-functional partners on assay strategy; maintain accurate experimental documentation and data records
Seniority
Mid-Senior level (Master's +3 years or Bachelor's +5 years)