Senior Research Scientist - Oligoneucleotides
Core
Senior Research Scientist leading analytical development, validation, and lifecycle management for oligonucleotide therapeutics in a GMP laboratory environment.
Role type
Senior Research Scientist (Analytical Development)
Builds
Analytical methods and specialty technologies for oligonucleotide drug development
Domain
Pharma / Analytical Chemistry / Oligonucleotides
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
analytical characterization of oligonucleotides, chromatographic techniques, mass spectrometric techniques, method development, method validation, GMP compliance, regulatory knowledge (ICH, USP, FDA), technical writing, project management, troubleshooting, SOP development
Preferred skills
none stated
Technologies
HPLC, UPLC, LCMS, GCMS
Responsibilities
Provide technical leadership for oligonucleotide analytical development activities including method development, validation, troubleshooting, and transfer; Independently plan scientific approaches to develop analytical methods meeting client requirements; Act as on-site Subject Matter Expert for analytical instrumentation; Evaluate technical options for analytical results quality and robustness; Design validation experiments to demonstrate method viability; Lead client discussions on project definitions and technical issues; Review protocols, study reports, and technical documents; Lead preparation and implementation of SOPs and quality systems; Review and analyze data for technical, quality, and compliance
Seniority
Senior, hands-on IC
