Scientist / Senior Scientist, Peptide Discovery
Core
Experimental validation of AI-generated peptide candidates across therapeutic programs (antifungal, antimicrobial, cardiometabolic) using cell culture-based functional, safety, and developability assays.
Role type
Senior Scientist, Peptide Discovery (hands-on IC) (via careerplan.io/jobs/69060e09-ebc5-4ee6-a218-8acaa72306d9-scientist-senior-scientist-peptide-discovery-at-basecamp-research)
Builds
Cell-based assays and data to inform AI-guided peptide discovery pipeline
Domain
Biotech / Peptide Discovery / AI-driven Therapeutic Design
Deliverable
production ML models
Required skills
Mammalian cell culture, Cytotoxicity/viability assays, Hemolysis assays, Cell permeability assays, Immunogenicity risk assessment, GLP-1R activation assays, Stable cell line establishment, Dose-response analysis, Peptide handling, Flow cytometry
Preferred skills
Biacore (SPR) testing, Peptide handling/reconstitution, High-throughput screening, Antifungal susceptibility testing, Gene editing tools knowledge, Technical savviness with AI tools
Technologies
CellTiter Blue, HTRF, ELISA, Luciferase reporter formats, Flow cytometry, Biacore (SPR)
Responsibilities
Perform mammalian cell culture; Design and execute cytotoxicity/viability and hemolysis assays; Run cell permeability and GLP-1R activation assays; Support immunogenicity risk assessment; Establish stable reporter/receptor cell lines; Generate dose-response curves; Prepare peptide stock solutions; Support fungal susceptibility assays; Design cell-based assay strategies; Collaborate with computational/AI teams
Seniority
Senior, hands-on IC
