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Principal Applied Scientist - AI for Life Sciences, AWS Applied AI Solutions - Life Sciences

Seattle, Washington, United States💼 Full-time🗓 2026-09-11 → 2026-09-26

Core

Define scientific direction and deliver production-scale AI solutions for drug discovery and clinical trial optimization using LLMs and agentic systems.

Role type

Principal Applied Scientist (LLM reasoning & Agentic AI for Life Sciences)

Builds

AI-guided protein engineering, antibody design tools, and agentic automation for clinical trial workflows

Domain

Life Sciences (Drug Discovery, Clinical Trials) + Frontier AI (LLMs, Agentic Systems)

Deliverable

production ML models | product features

Required skills

LLM reasoning & agentic AI architecture, model customization (fine-tuning, RLHF, domain adaptation), biological foundation models, Python, PyTorch/JAX, 0-to-1 product delivery

Preferred skills

Protein structure prediction/inverse folding, clinical data standards, mentoring senior scientists

Technologies

LLMs, Agentic AI, PyTorch, JAX, Retrieval Augmented Generation

Responsibilities

Set scientific vision for LLM reasoning in life sciences, innovate on agentic approaches for clinical protocols, develop model customization methods, adapt biological foundation models, solve open research problems in faithful reasoning, partner with domain experts to translate challenges, publish at top-tier venues, mentor applied scientists, collaborate with product/engineering to ship solutions

Seniority

Principal, hands-on IC with significant research contribution and mentorship

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