ScientistII, Discovery & Platform Innovation
Core
Design and optimize Prime Editing systems for new therapeutic targets, transitioning from in vitro to in vivo development to enable gene editing therapies.
Role type
Senior Scientist, Platform Technology & Innovation
Builds
Prime Editing systems and platform-level research capabilities for hematology, immunology, oncology, liver, and lung therapies.
Domain
Biotechnology / Gene Editing / Therapeutics
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
genome editing, prime editing, pegRNA design and screening, molecular biology, cell culture, next-generation sequencing, protein engineering, in vivo animal models, non-viral delivery (LNP), viral delivery (AAV)
Preferred skills
computational tools for protein engineering, AI/ML for sequence design, human biology knowledge, scientific communication, mentoring research associates
Technologies
Prime Editor protein constructs, mRNA constructs, LNP, AAV, in vitro cell culture systems, in vivo animal models
Responsibilities
Design and construct Prime Editing approaches for new targets; execute experiments to probe structure-function relationships; partner with cross-functional teams to translate platform advances; maintain engagement with scientific literature; communicate research findings and contribute to publications/patents; mentor research associates and interns
Seniority
Senior, hands-on IC with potential dotted-line oversight