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Research Scientist, Life Sciences (Chemistry)

San Francisco, CA💼 Full-time💰 $300,000–$300,000🗓 2026-08-14 → 2026-09-26

Core

Expert medicinal chemist closing the loop between AI-generated hypotheses and experimental data by designing, synthesizing, and characterizing small molecules.

Role type

Senior IC medicinal chemist (life sciences)

Builds

AI-designed molecules and experimental readouts for biological discovery

Domain

Life Sciences / Medicinal Chemistry / AI

Deliverable

physical/clinical work

Required skills

medicinal chemistry, small molecule synthesis, route selection, reaction optimization, purification, NMR, LC-MS, HPLC, SAR analysis, physicochemical property optimization

Preferred skills

lead optimization, contract research organization (CRO) management, computational chemistry, cheminformatics, Python/RDKit/pandas, AI/ML tools in life sciences

Technologies

NMR, LC-MS, HPLC, Python, RDKit, pandas

Responsibilities

Design multi-step synthetic routes and oversee execution; coordinate synthesis and biological evaluation with external partners; evaluate AI-designed molecules and proposed synthetic routes; apply medicinal chemistry principles for compound design; ensure high-quality experimental data and documentation

Seniority

Senior, hands-on IC

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