Medicinal Drug Design Lead, London
Core
Lead medicinal chemistry strategy and hit-finding for drug discovery programs, partnering with AI/ML teams to design novel molecules and optimize leads toward candidate nomination.
Role type
Senior Individual Contributor Medicinal Chemistry Lead
Builds
Novel drug molecules and optimized lead compounds for therapeutic areas
Domain
Biotechnology / Pharmaceutical Drug Discovery / AI-driven Medicinal Chemistry
Deliverable
production ML models
Required skills
Medicinal Chemistry, Synthetic Organic Chemistry, Structure-based Drug Design, DMPK optimization, CRO management, Hit identification strategies, Lead optimization, Candidate nomination, Strategic scientific planning
Preferred skills
ADCs, Peptides, Degraders, Proximity inducers, Hit generation using AI-driven methods
Technologies
AI/ML Drug Design Platforms, Generative AI models
Responsibilities
Drive early portfolio target selection and in silico hit-finding strategies; Lead medicinal chemistry strategy across active portfolio programs; Provide strategic input and technical direction to AI/ML platform teams; Represent the company externally with collaborators and CROs; Manage CRO resources and monitor KPIs; Prepare detailed scientific proposals and reports.
Seniority
Senior, hands-on IC with mentorship
