Senior Scientist, Culture Process Development
Core
Design and execute laboratory experiments in bench-top bioreactors and scale-down models to develop robust, scalable, and high-productivity manufacturing processes for recombinant proteins and other modalities for clinical trials.
Role type
Senior Scientist, Upstream Process Development
Builds
Manufacturing processes for recombinant proteins and other modalities for early- and late-phase human clinical trials
Domain
Biopharma / Bioprocess R&D
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Mammalian cell culture process development, process intensification, continuous manufacturing, scale-up/scale-down, metabolic pathway understanding, process kinetics, aseptic technique, experimental design, data analysis
Preferred skills
Perfusion bioreactor operations, high-throughput bioreactor platforms (ambr15, ambr250), process modeling, CFD, multivariate data analysis, AI/ML-based predictive modeling, Python programming, workflow automation
Technologies
ambr15, ambr250
Responsibilities
Design and execute experiments in scale-down models; serve as upstream technical lead for technology transfer to pilot and GMP facilities; document data in electronic lab notebooks and author technical reports for regulatory submissions; participate in team meetings on design of experiments and data interpretation
Seniority
Senior, hands-on IC
