Scientist II, Upstream Development for Protein Development and Manufacturing
Core
Developing and characterizing bacterial fermentation processes for protein production to create high-fidelity vaccines against bacterial diseases.
Role type
Scientist II, Upstream Process Development
Builds
Bacterial fermentation processes and protein production for vaccine candidates
Domain
Biotechnology / Vaccine Development / Upstream Processing
Required skills
Bacterial fermentation process development, Bioreactor operation and maintenance (Ambr 250), Aseptic techniques, Primary recovery unit operations (homogenization, centrifugation, depth filtration), Scale-up and scale-down modeling, Design of Experiments (DoE), SOP authoring, Data analysis and presentation
Preferred skills
Pilot scale fermentation and recovery equipment experience, Late-stage process characterization, Regulatory knowledge of biotherapeutics
Technologies
Ambr 250, Electronic notebooks
Responsibilities
Develop and characterize upstream fermentation processes, Operate and maintain bioreactors, Develop recipe scripting for fed-batch fermentation, Provide engineering support for scale-down models, Author SOPs and process documentation, Analyze and present fermentation data, Mentor junior team members
Seniority
Mid-level Scientist (2-5 years post-PhD or 7-10 years post-BS)
