Principal Scientist, Cell Culture Development
Core
Lead upstream process development for biologics, guiding recombinant products from early development to manufacturing readiness.
Role type
Principal Scientist, Cell Culture Development
Builds
Upstream bioprocesses for recombinant protein products
Domain
Biologics / Recombinant protein technology
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Cell culture process development, Upstream process optimization, Scale-up strategies, Experimental design and execution, Regulatory documentation, Cross-functional collaboration, Team mentorship
Preferred skills
Mammalian cell culture (CHO systems), Media development, Metabolic modelling, Bioreactor scale-down, Technology transfer
Technologies
CHO systems, Bioreactors
Responsibilities
Provide scientific leadership in cell culture process development and scale-up; Design and execute upstream development strategies across high-throughput and mid-scale platforms; Lead experimental planning, execution, and data interpretation; Support process development from clone selection to process characterization; Guide and mentor team members; Contribute to regulatory documentation and submissions; Collaborate on tech transfer and manufacturing readiness.
Seniority
Principal, hands-on IC with leadership
