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ML Scientist I/II, Nucleic Acid Design

San Francisco, CA💼 Full-time💰 $176,000–$176,000🗓 2026-07-27 → 2026-09-26

Core

Develop ML models and design strategies for RNA and DNA sequence engineering, including regulatory element design, sequence optimization, and generative modeling to connect sequence design to biological function.

Role type

Senior IC machine learning scientist (nucleic acid design)

Builds

Production ML models for de novo sequence generation, property prediction, and active learning strategies integrated into an autonomous science platform.

Domain

Biotechnology / Computational Biology / Machine Learning

Deliverable

production ML models

Required skills

Machine learning model development, sequence modeling, generative modeling, active learning, PyTorch, JAX, biological mechanism reasoning, experimental design collaboration

Preferred skills

Regulatory element design, sequence-to-expression modeling, RNA secondary structure modeling, high-throughput experimental data analysis, therapeutic context experience

Technologies

PyTorch, JAX

Responsibilities

Build ML models for RNA and DNA sequence design across regulatory and coding contexts; Develop methods for de novo generation and diverse set selection; Investigate biological mechanisms of designed sequences; Partner with experimental scientists to propose assays and validation strategies; Collaborate on integrating models into agent-driven frameworks; Share research findings externally.

Seniority

Senior, hands-on IC

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