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Senior Machine Learning Scientist I, Model-Driven Optimization

Somerville, MA💼 Full-time🗓 2026-07-14 → 2026-07-31

Core

Building ML methods, data strategies, and closed-loop systems for lab-in-the-loop protein optimization to discover and optimize therapeutic proteins.

Role type

Senior IC machine learning scientist (model-driven optimization)

Builds

Production ML models, data workflows, and agentic systems for protein design

Domain

Biomedical / Protein engineering / Generative biology

Deliverable

production ML models

Required skills

Probabilistic machine learning, Bayesian optimization, active learning, experimental design, Python, PyTorch/JAX, systems thinking, multi-objective optimization

Preferred skills

Protein design, antibody engineering, deep learning (transformers), LLM agents, high-throughput screening

Technologies

PyTorch, JAX, LLMs

Responsibilities

Develop ML methods for lab-in-the-loop protein optimization; Shape data-generation strategies for experimental campaigns; Build and apply LLM-enabled agentic workflows; Design and maintain production-quality ML models and data workflows; Partner with engineering to integrate scalable platform capabilities; Collaborate with wet-lab scientists to ground models in experimental reality; Define technical direction and milestones for cross-functional programs.

Seniority

Senior, hands-on IC

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