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Scientist I / Scientist II, Computational Protein Generation

Somerville, MA💼 Full-time🗓 2026-07-08 → 2026-07-31

Core

Develop and productionize de novo protein generation protocols and optimization techniques using machine learning to advance therapeutic pipelines.

Role type

Computational Scientist (de novo protein design)

Builds

Production-ready ML models and tools for protein generation

Domain

Biomedicines / Structural Biology / Machine Learning

Deliverable

production ML models

Required skills

Structural biology intuition, de novo protein design methods, generative modeling, biophysical metrics design, model benchmarking, agentic AI tool integration, Python/software engineering

Preferred skills

Experience with design-build-test-learn cycles, knowledge of therapeutic mechanisms of action

Technologies

Agentic AI tools, proprietary Generate platform

Responsibilities

Develop and validate de novo protein generation protocols; Define and implement in silico biophysical and functional metrics; Benchmark foundation models for therapeutic applications; Propose new therapeutic strategies via de novo tools; Partner cross-functionally to drive therapeutic development; Advance state of the art in sequence–structure–function understanding; Integrate agentic tools into workflows; Build production-quality code

Seniority

Individual Contributor (IC)

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