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Principal, Machine Learning Engineer

San Francisco, CA💼 Full-time💰 $252,000–$252,000🗓 2026-05-14 → 2026-07-31

Core

Design, build, and scale ML infrastructure for generative models and reasoning frameworks powering automated scientific discovery in life sciences.

Role type

Principal, hands-on IC Machine Learning Engineer

Builds

Large-scale training pipelines, distributed compute systems, and production ML serving infrastructure for biological sequence design and molecular structure prediction.

Domain

Life Sciences (Biotech/Pharma) + Machine Learning Systems Engineering

Deliverable

production ML models

Required skills

Distributed training infrastructure, large-scale GPU cluster management, system design, production-grade code, CI/CD, observability, PyTorch/JAX/TensorFlow, cross-functional collaboration with researchers

Preferred skills

Generative models for biological sequences, agentic frameworks, active learning loops, open-source ML contributions, life science domain familiarity

Technologies

PyTorch, JAX, TensorFlow, AWS, GCP

Responsibilities

Design and optimize large-scale training pipelines for generative models; own production ML systems end-to-end including deployment and monitoring; architect ML infrastructure for rapid iteration; drive engineering standards and tooling; translate research prototypes into robust production systems.

Seniority

Principal, hands-on IC

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