Scientist II, Complex In Vitro Model
Core
Design, execute, and interpret in vitro studies to characterize drug candidate molecules and validate drug targets using complex cellular systems.
Role type
Scientist II, Complex In Vitro Model
Builds
Drug discovery programs for inflammatory and auto-immune diseases
Domain
Immunology / Biochemistry / Cell Biology
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
culturing primary human immune cells, immortalized cell lines, organ/tissue cultures, iPSCs, 3D cellular systems, co-culture, cell signaling analysis, phosphoprotein analysis, gene reporter assays, ELISA/MSD, alphaLISA, HTRF, PCR, multicolor flow cytometry, high content microscopy, statistics, curve-fitting software, automation
Preferred skills
expertise in organoids or organ-on-chip models, experience with differentiated cells
Technologies
Microsoft Excel, GraphPad Prism
Responsibilities
Design and perform biochemical and cellular studies of drug potency and mechanism of action; analyze and interpret quantitative data; read and apply relevant scientific literature; maintain accurate research records
Seniority
Mid-level, hands-on IC
