Senior Scientist, Antibody Repertoire Sequencing & Discovery
Core
Optimizing and expanding antibody repertoire sequencing (RepSeq) capabilities and developing innovative methods for therapeutic antibody discovery against complex targets.
Role type
Senior Scientist, Antibody Repertoire Sequencing & Discovery
Builds
Therapeutic antibodies for Immunology, Neurology, and Oncology diseases
Domain
Biopharmaceuticals / Immunology / Next-Generation Sequencing
Deliverable
production ML models | product features
Required skills
Immunoglobulin genetics and antibody biology, B cell biology, NGS library preparation and data capture, molecular cloning and primer design, computational analysis of RepSeq data, predictive AI/ML tools and protein language models
Preferred skills
Non-human/non-murine immunogenetics, bioinformatics of large DNA/protein datasets, in vitro antibody discovery libraries, mammalian cell culture, immunoassays (ELISA, flow cytometry)
Technologies
Illumina (NextSeq, MiSeq), PacBio, PipeBio, Geneious, Sequencher
Responsibilities
Generate original technical ideas and research strategies for RepSeq and analysis, collaborate with computational scientists to optimize repertoire analysis and apply repertoire-guided machine learning, generate, document, and archive repertoire data with metadata, analyze and interpret results in scientific context, present findings at team meetings
Seniority
Senior, hands-on IC
