Lead Scientist - Large Molecules
Core
Define scientific workflows and modeling strategies for antibody-antigen co-folding, binder prediction, and antibody developability within federated drug discovery networks.
Role type
Senior domain scientist (large molecules/biologics)
Builds
Federated AI networks for drug discovery (co-folding, ADMET, antibody developability)
Domain
Pharmaceutical R&D, Structural Biology, Biologics
Deliverable
Research & Scientific Strategy
Required skills
Antibody engineering, Structural biology, Immunology, Protein engineering, AI/ML fluency, Scientific workflow design, Stakeholder management
Preferred skills
OpenFold/AlphaFold/Boltz familiarity, Antibody developability assays, Pharma partner collaboration, Publication record
Technologies
OpenFold, AlphaFold, Boltz, ESM
Responsibilities
Define scientific workflow and evaluation strategy for large molecule programs; Translate biological requirements from pharma partners into technical inputs for ML teams; Review model outputs against structural biology knowledge to flag biological inconsistencies; Drive adoption of large molecule models with pharma partners; Represent scientific perspective in partner conversations; Stay current on large molecule AI/ML landscape.
Seniority
Senior, hands-on IC
