Executive Director, AIRx Program Lead: Biologics
Core
Lead end-to-end scientific and strategic direction of 2–3 large molecule discovery programs in an AI-forward environment to deliver candidates to the clinic at speed.
Role type
Senior IC Executive Director, Biologics Program Lead
Builds
Large molecule drug candidates (antibodies, bispecifics, fusion proteins) for clinical development
Domain
Biopharmaceuticals / Large Molecule Discovery
Required skills
Biologic drug discovery strategy, protein engineering, AI/ML for protein design, CMC considerations, PK/PD modeling, CRO/CDMO management, business acumen
Preferred skills
None explicitly stated as preferred beyond the required track record
Technologies
AI/ML platforms, protein design tools, computational platforms
Responsibilities
Lead and manage multiple biologic drug discovery projects from modality selection through IND filing; Define and evolve program strategy for large molecule modalities; Evaluate and prioritize biologic candidates based on scientific and commercial considerations; Lead rapid AI-enabled Design and Test cycles for protein engineering; Drive sequence optimization and candidate selection; Partner with Clinical and Translational teams to refine asset strategy; Manage external CROs and CDMOs; Represent Takeda externally for AIRx Biologics and evaluate external opportunities; Ensure programs are delivered at pace with disciplined cost stewardship
Seniority
Executive Director, strategic leadership
