Scientist 3, Functional Immunogenomics
Core
Develop and deploy molecular engineering technologies, biologically relevant models, and state-of-the-art genomics, functional, and imaging read-outs to interrogate complex immunological disease mechanisms at scale.
Role type
Senior IC functional immunogenomics scientist
Builds
Novel molecular mechanisms, target candidates, and cell therapy strategies for immune-mediated diseases
Domain
Biopharma / Functional Genomics / Immunology
Deliverable
production ML models | product features | research
Required skills
Immunology (primary immune cell culture, functional assays), Molecular Engineering (CRISPR, deep mutational scanning, lineage tracing, molecular recorders), High-content genomics (NGS, single-cell genomics, proteomics, imaging), Flow cytometry, Experimental design and execution, Project management
Preferred skills
In vivo experience, Data analysis (R, Python), iPSC experience
Technologies
CRISPR, CRISPRko, CRISPRi/a, base editing, NGS, single-cell genomics, proteomics, flow cytometry, R, Python
Responsibilities
Develop and deploy molecular engineering technologies and biologically relevant models; Interrogate complex immunological disease mechanisms at scale; Identify novel molecular mechanisms, target candidates, and cell therapy strategies; Manage multiple research projects in parallel; Collaborate with multidisciplinary teams (immunology, cell therapy, genomics, computational biology, AI/ML)
Seniority
Senior, hands-on IC