Principal Data Scientist (AI-assisted Clinical Development)
Core
Building and deploying AI/ML-powered digital solutions to transform medicine development by integrating statistical capabilities into clinical decision-making tools.
Role type
Principal Data Scientist (AI/ML strategy & productization)
Builds
Scalable, ethical, and compliant AI/ML tools for clinical development and decision support
Domain
Biopharmaceuticals / Clinical Development / AI & Machine Learning
Deliverable
production ML models | product features (via careerplan.io/jobs/202604-108773-1-principal-data-scientist-ai-assisted-clinical-development-at-roche)
Required skills
Advanced statistical modeling, Machine Learning, Simulation studies, Python, R, Bayesian methods, Causal inference, High-dimensional data analysis, Model deployment in regulated environments, Algorithmic fairness evaluation
Preferred skills
Technical leadership, Agile software development, GenAI product prototyping, Evidence synthesis methods, Probabilistic programming (Stan, PyMC), Cloud-native ML architectures, Regulatory knowledge in pharma
Technologies
Python, R, scikit-learn, TensorFlow, Pytorch, Stan, PyMC, brms
Responsibilities
Design and productize simulation studies for innovative trial designs; Develop scalable pipelines for data processing and model deployment; Optimize model performance and mitigate bias in deployed systems; Co-lead architectural design of ML and GenAI systems; Publish novel methodologies in high-impact venues; Lead cross-functional data science efforts impacting portfolio strategy
Seniority
Principal, hands-on IC with strategic influence
