Biologe (m/w/d)
Core
Conducting research projects in cancer immunotherapy, specifically generating and characterizing gene transfer vectors (lentiviral, AAV, nanoparticles) for CARs or BITEs in T-lymphocytes.
Role type
Research Assistant (IC)
Builds
Gene transfer vectors and modified T-lymphocytes for therapeutic applications
Domain
Life Sciences / Biotechnology / Cancer Immunotherapy
Required skills
Molecular biology, Cell biology, Immunology, Oncology, Vector generation, Primary cell culture, In vitro assays, In vivo mouse models
Preferred skills
Experience with receptor-targeted vectors, DARPins, Point mutations, Ligand engineering
Technologies
Lentiviral vectors, AAV vectors, Nanoparticles, DARPins, CARs, BITEs, Cell lines, Organoids
Responsibilities
Conducting research projects in cancer immunotherapy, Targeted genetic information introduction for CARs or BITEs in T-lymphocytes, Generation and characterization of gene transfer vectors, Evaluation of vector selectivity, biodistribution, and activity in vitro and in mouse models