Senior Scientist, Cell Therapy Research, Molecular Immunobiology and Discovery Team (In vivo CAR-T)
Core
Develop and validate technologies to efficiently generate potent CAR-T cells by building next-generation lentiviral vectors and assessing delivery strategies.
Role type
Senior Scientist, Molecular Immunobiology and Lentivirology
Builds
Next-generation lentiviral vectors and engineered cell-based therapies
Domain
Biotechnology / Cell Therapy / Molecular Immunobiology
Required skills
Lentiviral vector biology, CAR-T cell biology, in vivo and in vitro T-cell assessment, flow cytometry, protein expression analysis, experimental design, data interpretation
Preferred skills
Lentiviral vector engineering, T-cell activation pathway knowledge, multi-parameter flow cytometry, project management, strategic decision support
Technologies
Lentiviral vectors, MSD, IncuCyte, flow cytometry
Responsibilities
Plan and implement hypothesis-driven studies for lentiviral vector platform building; Develop strategies to increase yield and throughput of vector platforms; Interface with immunologists to assess T-cell activation and CAR-T phenotype; Interpret complex datasets to enable scientific decision-making; Provide technical insights on vector evaluation; Recommend department-level strategic decisions; Mentor junior colleagues; Design experiments and communicate progress for Go/No Go decisions.
Seniority
Senior, hands-on IC with mentorship