NBE DMPK Lead (all genders), limited for 2 years
Core
Define DMPK strategy for novel biological entities (ADCs, AOCs, multispecific biologics) and integrate PK, immunogenicity, and bioanalytical approaches to de-risk clinical development.
Role type
Senior IC drug metabolism and pharmacokinetics (DMPK) lead
Builds
Next-generation biotherapeutics
Domain
Life Sciences / Biopharmaceuticals
Deliverable
production ML models | product features
Required skills
Drug metabolism and pharmacokinetics (DMPK), quantitative modeling and simulation (M&S), population PK analysis, bioanalytical assay development, translational science, regulatory strategy for biotherapeutics, Python or R programming, AI/ML in drug development
Preferred skills
ADC/AOC/multispecific biologics expertise, German or Italian language proficiency
Technologies
M&S tools, population PK software, QSP platforms, Python, R
Responsibilities
Define DMPK strategy for each molecule, integrate PK and immunogenicity data, generate data-driven insights for molecular design, translate preclinical findings into human dose predictions, guide cross-functional project teams
Seniority
Senior, hands-on IC
