Senior Scientist, Fermentation - IR&D, Product Development
Core
Lead upstream fermentation development, clone selection, and technology improvements for novel vectors (AAV/lentiviral) to support biologics manufacturing.
Role type
Senior Scientist, Fermentation (Upstream Process Development)
Builds
Novel vectors for cell and gene therapies
Domain
Biologics / Biopharmaceuticals / Upstream Fermentation
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
E. coli strain selection, clone selection, plasmid stability assessment, transfection studies, high-throughput screening, fermentation optimization, media formulation, lysis strategies, bioreactor operation, regulatory document preparation
Preferred skills
Mammalian cell culture (HEK293, CHO), scale-up to 50L+ bioreactors, recombinant protein expression, gene therapy vector manufacturing
Technologies
DASGIP, Eppendorf BioFlo, ambr15, UpTempo
Responsibilities
Lead platform fit assessment for novel vectors, execute clone selection and strain selection, evaluate novel plasmid vectors, conduct transfection and high-throughput screening, transfer fermentation processes to GMP manufacturing, improve fermentation processes and media, maintain plasmid inventory and lab operations, troubleshoot technical challenges
Seniority
Senior, hands-on IC
