Senior Research Associate – Scientist II, Molecular Biology & Viral Vector Platforms
Core
Accelerates cell and genome therapy research by enabling reliable generation, characterization, and improvement of lentiviral vectors for discovery and preclinical studies.
Role type
Senior Research Associate / Scientist II (Molecular Biology & Viral Vector Platforms)
Builds
Lentiviral vectors, DNA constructs, variant libraries, and immune cell workflows for screening and preclinical studies.
Domain
Biotechnology / Cell and Gene Therapy / Molecular Biology
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Molecular cloning and nucleic-acid workflows, Library design/build for screening or display, Lentivirus production and titering/QC, Mammalian tissue culture in BSL-2, qPCR/RT-qPCR and multi-parameter flow cytometry, ELN documentation
Preferred skills
T cell activation and lentiviral transduction, NGS-enabled library readouts, Viral vector scale-up/down and downstream handling
Technologies
HEK293T, Gibson/In-Fusion, PCR/qPCR, ddPCR, p24 assays, BSL-2 facilities, Single-use bioreactors, Wave bioreactors, TFF
Responsibilities
Design, build, and QC DNA constructs and variant libraries for screening; Produce, titer, and QC lentivirus from HEK293T; Perform mammalian tissue culture in BSL-2; Execute immune cell workflows; Run qPCR/RT-qPCR and multi-parameter flow cytometry; Maintain rigorous ELN documentation
Seniority
Senior, hands-on IC
