Senior Data Scientist, CompBio

South San Francisco, CA💼 Full-time💰 $183,000–$183,000🗓 2026-08-28 → 2026-09-25

Core

Synthesize multimodal biological data (omics, imaging) to identify therapeutic targets, elucidate disease mechanisms, and validate biomarkers for drug development.

Role type

Senior computational biologist (compbio) with deep data modality expertise

Builds

Therapeutic target hypotheses, validated biomarkers, and mechanistic insights for drug discovery

Domain

Biotech / Computational Biology / Drug Discovery

Deliverable

production ML models | product features

Required skills

single-cell RNA-seq analysis, fluorescence microscopy, spatial proteomics, statistical modeling, Python (NumPy, pandas), molecular biology knowledge

Preferred skills

experience with label-free microscopy, transcriptomics, perturbation screen analysis

Technologies

Python, NumPy, pandas

Responsibilities

Synthesize insights from microscopy, spatial proteomics, and RNA-seq to uncover disease mechanisms; Analyze in vitro model data to identify potential therapeutic targets; Calibrate analysis tools and workflows; Partner with experimental biologists to design and optimize experiments

Seniority

Senior, hands-on IC

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About insitro

insitro is a drug discovery and development company using machine learning (ML) and data at scale to decode biology for transformative medicines. At the core of insitro’s approach is the convergence of in-house generated multi-modal cellular data and high-content phenotypic human cohort data. We rely on these data to develop ML-driven, predictive disease models that uncover underlying biologic state and elucidate critical drivers of disease. These powerful models rely on extensive biological and computational infrastructure and allow insitro to advance novel targets and patient biomarkers, des