CareerPlan

Lead/ Senior Machine Learning Scientist, Integrative Phenotyping

South San Francisco, CAFull-time$183k–$224k2026-11-02 → 2026-11-10
Hybrid · United States

Core

Develop and deploy ML approaches to build precise phenotypes from large-scale multimodal datasets (clinical imaging, EHRs, multi-omics) to understand patient state, predict clinical endpoints, and identify therapeutic targets.

Role type

Senior IC machine learning scientist (integrative phenotyping)

Builds

Production ML models for patient state characterization and target discovery

Domain

Biopharma / Computational Biology / Clinical Data Science

Deliverable

production ML models

Required skills

Multimodal ML, Clinical imaging analysis, EHR processing, Multi-omics integration, Causal inference, Python, Deep learning frameworks, Cloud engineering

Preferred skills

Cardiovascular disease, Neuroscience, Metabolism domain knowledge

Technologies

Python, Deep learning frameworks, Cloud environments

Responsibilities

Develop ML methods to extract biological insight from high-dimensional human cohort data; Build models to characterize patient state and predict clinical endpoints; Engineer reusable platform components; Integrate causal evidence across phenotypic readouts to select therapeutic targets; Partner with clinical teams to develop biomarkers; Associate human genetics with ML-derived phenotypes.

Seniority

Senior, hands-on IC