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Snr Data Scientist, Computational Genomics/DNA Modelling

London💼 Full-time🗓 2026-07-03 → 2026-09-26

Core

Senior data scientist developing computational models to connect genetic variation and regulatory DNA sequences to downstream molecular phenotypes and disease biology for target discovery.

Role type

Senior IC data scientist (computational genomics/DNA modelling)

Builds

Production ML models for variant effect prediction, regulatory activity modelling, and representation learning for genomic data

Domain

Biotech / Computational Genomics / Machine Learning

Deliverable

production ML models

Required skills

DNA language models, genomic foundation models, transformer-based sequence models, statistical machine learning, probabilistic modelling, statistical genetics methods (fine-mapping, colocalisation), Python, R, high-performance computing

Preferred skills

single-cell transcriptomics, patient-derived datasets, interdisciplinary biotech/pharma experience, integrating ML with genomics/perturbation datasets, 3D genome/chromatin interaction data (Hi-C, Capture-C)

Responsibilities

Develop and implement ML models for DNA sequence and genetic variation; Build and benchmark sequence-to-function models; Integrate sequence representations with transcriptomic/epigenomic datasets; Partner with experimental researchers to validate hypotheses; Contribute to scientific publications and documentation

Seniority

Senior, hands-on IC

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