Associate Scientist - Upstream Cell Culture
Core
Designs and executes upstream process development studies for Adeno-associated virus (AAV) and Lentiviral vector (LVV) production to support clinical manufacturing of cell gene therapy products.
Role type
Associate Scientist - Upstream Cell Culture
Builds
AAV and LVV manufacturing technologies, processes, and scale-up capabilities for Novartis cell gene therapy products.
Domain
Biotechnology / Gene Therapy / Viral Vector Manufacturing
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Bioreactor operation (ambr, bench-top, pilot scale), Statistical analysis, Design of Experiment (DoE), Data-driven decision making
Preferred skills
Viral gene therapy knowledge, AAV process development experience
Technologies
ambr® bioreactors, bench-top bioreactors, pilot scale bioreactors
Responsibilities
Design and execute gene therapy upstream process development studies; Support early development and late-stage process characterization/scaling; Analyze experimental data with statistical mindset; Conduct laboratory studies for media development and process optimization; Perform experiments at different scales for pre-clinical, clinical, and commercial programs; Author technical reports and present results; Collaborate with cross-functional groups
Seniority
Associate, hands-on IC