Associate Director, ADC platform in Oncology Drug Discovery
Core
Lead scientific strategy for antibody-drug conjugate (ADC) discovery, focusing on payload selection, linker design, and conjugation approaches to advance targeted therapeutics.
Role type
Associate Director, ADC platform strategy
Builds
Next-generation ADC concepts and differentiated payload-linker technologies
Domain
Oncology drug discovery / Chemical biology
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
ADC payload expertise, linker and conjugation technologies, ADC biology (tumor targeting, internalization, trafficking), program strategy integration, cross-functional leadership, experimental design
Preferred skills
Mechanism of action analysis, resistance biology, bystander activity assessment, IP landscape monitoring
Technologies
Site-specific conjugation, chemical biology tools, pharmacology platforms
Responsibilities
Lead scientific strategy for ADC payload selection and linker design; Partner with chemistry, biology, and CMC teams to advance ADC programs; Evaluate and prioritize novel payloads and linker technologies; Provide biology-driven insights into mechanism of action and therapeutic index; Design experimental strategies to assess ADC activity and resistance mechanisms; Mentor scientists and contribute to a collaborative research environment
Seniority
Senior, hands-on IC with strategic leadership
