Lead Analytical Scientist - Mass Spectrometry
Core
Lead complex analytical projects for therapeutic protein characterisation, focusing on mass spectrometry and biocomparability studies.
Role type
Senior IC analytical scientist (mass spectrometry)
Builds
Product characterisation data, reference standards, and regulatory-compliant analytical reports for biotherapeutics.
Domain
Biopharmaceuticals / Protein Chemistry
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
LC-MS/MS, protein primary structure analysis, charge variant analysis, post-translational modification analysis, method development, method validation, method troubleshooting, root cause analysis, project leadership, mentoring
Preferred skills
RP, SEC, icIEF, capillary electrophoresis
Technologies
LC-MS/MS, RP, SEC, icIEF
Responsibilities
Lead complex analytical projects from planning through execution; develop, optimise and troubleshoot analytical methods for therapeutic proteins; apply mass spectrometry to investigate protein structure and modifications; provide technical leadership and training to scientists; perform and review analytical testing for product characterisation and comparability studies; collaborate with internal teams and external customers; drive continuous improvement in analytical capabilities.
Seniority
Senior, hands-on IC