Principal Research Scientist II - Analytical Development
Core
Lead and mentor scientists in separation-based assays (HPLC, capillary electrophoresis) to support late-stage biologics product development, characterization, and GMP manufacturing.
Role type
Principal Research Scientist II (Analytical Development)
Builds
Biologics mAbs, multi-specifics, antibody-drug conjugates, and fusion proteins for late-stage clinical programs
Domain
Biopharmaceuticals / Biologics / Analytical Chemistry
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
HPLC, capillary electrophoresis, mass spectrometry, ELISA, method development, regulatory submission authoring, technical writing, project management, team leadership
Preferred skills
Experience with multi-specifics and antibody-drug conjugates, automation of high-throughput methods
Technologies
HPLC, capillary electrophoresis, mass spectrometry, ELISA
Responsibilities
Lead and mentor scientists specializing in separation-based assays; Serve as process analytics lead for mAbs and DS; Act as subject matter expert for separation-based methods; Evaluate and select effective analytical technologies; Author and review analytical sections of IND/BLA filings; Provide guidance to peers on analytical strategy development
Seniority
Principal, hands-on IC with mentorship