Lead Scientist, R&D (Upstream)
Core
Design and lead experimental work programs for process analytical technologies (PAT) in upstream unit operations to produce monoclonal antibodies, bispecific antibodies, and other modalities.
Role type
Lead Scientist, R&D (Upstream Processing)
Builds
Monoclonal antibodies (mAb), bispecific antibodies (bsAb), and non-mAb modalities (Fab, enzyme)
Domain
Biopharmaceutical manufacturing, mammalian cell culture
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
spectroscopic modeling, fermentation, mammalian cell culture, process control (fed-batch, intensified fed-batch, perfusion), complex biochemical pathways, project leadership
Preferred skills
Biochemistry, Chemical Engineering, or Biology degree
Technologies
spectroscopic modeling tools, cell culture systems
Responsibilities
Lead complex USP programs with full accountability for project results, drive scientific innovation and process robustness for PAT experiments, oversee daily USP activities including inoculum subcultures and cell culture operations, solve complex problems and guide technical decisions, foster high-performing team culture through coaching and leadership, escalate critical issues to Subject Matter Experts
Seniority
Senior, hands-on IC with project-level leadership
