Senior Scientific Director, Protein Engineering
Core
Provide scientific and strategic leadership for protein engineering and biologics discovery to enable next-generation biotherapeutics for neurological, psychiatric, endocrine, and immunological disorders.
Role type
Senior Scientific Director, Protein Engineering
Builds
Next-generation biotherapeutics (antibody and protein therapeutics) for under-addressed neurological, psychiatric, endocrine, and immunological disorders
Domain
Biopharmaceuticals / Protein Engineering / Biologics Discovery
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
protein engineering, antibody engineering, structure-function relationships, protein conjugation technologies, multispecific antibodies, antibody-drug conjugates, molecular design, lead optimization, developability assessment, candidate selection, recombinant protein expression, purification, biochemical characterization, biophysical characterization, display platforms, affinity maturation, engineered scaffolds, CRO management, strategic partnerships, scientific strategy, team leadership
Preferred skills
computational protein design, machine learning-enabled protein engineering, AI-assisted molecular design, high-throughput screening, protein display platforms, regulatory expectations for biologics IND submission
Technologies
LC-MS, display platforms, affinity maturation platforms, engineered scaffolds
Responsibilities
Lead and provide strategic direction for the Protein Engineering function; Guide discovery programs from target assessment through lead generation and candidate selection; Drive innovation in antibody and protein engineering technologies; Lead, mentor, and develop an existing high-performing team of protein engineers; Partner with multidisciplinary teams to accelerate biologics programs; Present scientific strategy and program updates to senior leadership and external audiences
Seniority
Senior, hands-on IC with strategic leadership
