Assoc. Scientist,Post Doc Fellow
Core
Design and execute single-cell transcriptomics experiments integrating cellular models of cancer and functional perturbation to investigate cancer biology, target mechanisms, and therapeutic biomarkers. (via careerplan.io/jobs/R421017-assoc-scientistpost-doc-fellow-at-msd)
Role type
Postdoctoral Fellow, Single-Cell Transcriptomics for Target and Biomarker Discovery
Builds
Novel treatments/therapeutics and methodological advances in single-cell technologies
Domain
Biopharmaceutical research, Cancer biology, Single-cell transcriptomics
Required skills
Mammalian cell biology, Molecular biology techniques, Functional perturbation techniques (RNAi, CRISPR), High-dimensional transcriptomics workflows, Data analysis, Scientific publication
Preferred skills
RNA/DNA QC platforms, Complex cellular models (organoids), Automation and high-throughput screening, Cancer biology knowledge
Technologies
RNAi, CRISPR, qRT-PCR, Immunoassays, Western blots, Microscopy, High-content imaging, Single-cell RNA-seq, Bulk RNA-seq
Responsibilities
Designing and executing loss-of-function and gain-of-function perturbation studies, Characterising effects of target perturbation using molecular and cellular assays, Developing and deploying high-throughput single-cell RNA-seq workflows, Partnering with data scientists to analyse omics datasets, Developing analytical strategies to uncover disease mechanisms, Investigating target mechanisms of action
Seniority
Postdoctoral Fellow, Independent Researcher