Principal Scientist – Multiscale Separations Team Lead
Core
Lead purification and analytical chromatography capabilities to support drug development pipelines for small molecules, peptides, ADCs, and biologics.
Role type
Principal Scientist (Laboratory Leadership & Technical Strategy)
Builds
Purification workflows, analytical separation solutions, and digital/automation-enabled laboratory capabilities
Domain
Pharmaceutical/Biotechnology - Separation Sciences/Analytical Chemistry
Required skills
HPLC/SFC/Preparative Chromatography, Impurity Isolation, Chiral Separations, LC-MS, LIMS/Automation Workflows, Method Development, Technical Mentoring, Cross-functional Collaboration
Preferred skills
Mass Spectrometry (MS-directed purification), Laboratory Capital Planning, CDMO Collaboration, Infrastructure Strategy, External Scientific Engagement
Technologies
HPLC, SFC, uHPLC, LCMS, PDA, Multi-angle light scattering, Charged aerosol detection, LIMS
Responsibilities
Provide scientific leadership in chromatographic purification and analytical separations; Develop and implement innovative technologies and automation workflows; Mentor and develop scientific staff; Partner with cross-functional teams on project strategy and capability roadmaps; Oversee laboratory operations, instrumentation strategy, and regulatory compliance. (via careerplan.io/jobs/R420285-principal-scientist-multiscale-separations-team-lead-at-msd)
Seniority
Principal, hands-on IC with strategic oversight
