Principal Scientist, Translational Clinical Biomarkers
Core
Lead strategic and scientific biomarker design, execution, and analysis across Cardiovascular & Metabolic and Infectious Diseases/Vaccines programs from early to late clinical development.
Role type
Principal Scientist, Translational Clinical Biomarkers
Builds
Decision-centric biomarker strategies and high-value evidence informing program development decisions
Domain
Biopharmaceuticals, Cardiovascular & Metabolic diseases, Infectious Diseases, Vaccines
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Translational medicine, Biomarker science, Drug development, Disease biology, Pharmacodynamics, Clinical study design, Data synthesis, Strategic thinking, Cross-functional leadership, Scientific communication
Preferred skills
Precision medicine, Patient stratification, Immuno-oncology, Multidimensional data analysis, Mentoring
Technologies
None explicitly stated
Responsibilities
Develop integrated biomarker strategies for CVM and ID/Vaccines programs; Translate disease biology into translational hypotheses; Define biomarkers to inform proof of biology, target engagement, and go/no-go decisions; Partner with cross-functional teams including Discovery, Clinical Development, and Regulatory; Interpret complex datasets to provide actionable recommendations; Evaluate emerging biomarker technologies; Communicate strategies and results to stakeholders; Mentor biomarker scientists.
Seniority
Principal, strategic leadership & mentorship
