Senior Medical Director, Translational Medicine & Early Clinical Development
Core
Leading early development and mechanistic clinical studies for metabolic liver and cardiometabolic therapeutics, integrating clinical and biomarker data to inform go/no-go decisions and label strategy.
Role type
Senior physician-scientist medical director (translational medicine & early clinical development)
Builds
First-in-human and early proof-of-concept studies (mechanistic, indication-expansion) for MASH and cardiometabolic conditions
Domain
Biopharmaceuticals, metabolic liver disease (MASH), cardiometabolic disorders
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
clinical trial leadership (FIH/PoC), translational medicine strategy, biomarker integration, regulatory agency interaction, cross-functional team leadership, scientific presentation
Preferred skills
hepatology/gastroenterology/endocrinology/cardiology background, metabolic liver or cardiometabolic disease experience
Technologies
none stated
Responsibilities
Serve as global medical lead/monitor for early phase studies; lead design of study concepts and protocols; provide ongoing medical oversight of trials; define and own translational strategy from preclinical to late-stage; chair early asset teams; present program work to executive team and board; mentor junior physicians and PhD scientists
Seniority
Senior, hands-on IC with strategic leadership