Principal Scientist, Upstream Process Development Group Lead
Core
Lead strategic initiatives and design scalable upstream cell-culture processes for biologics in early- and late-stage clinical development.
Role type
Principal Scientist, Upstream Process Development Group Lead
Builds
Robust, scalable upstream bioprocesses and process characterization data for commercialization
Domain
Biologics, Bioprocess Engineering, Cell Culture
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Upstream bioprocessing, Cell-culture process development, Bioreactor scale-up and scale-down, Cell metabolism, CMC development, Cross-functional team leadership, Regulatory filings, Process characterization, Technology transfer, Scientific strategy
Preferred skills
Continuous biomanufacturing, Perfusion process development, Media/feed development, High-throughput experimentation, Process modeling (omics/metabolic flux), Microbial fermentation
Technologies
Bioreactors, FEA, Omics tools, Metabolic flux analysis, Automation
Responsibilities
Shape and drive innovation across the biologics pipeline; Solve scientific and technical challenges across multidisciplinary teams; Lead development of scalable upstream processes; Improve process efficiency and cost-effectiveness; Collaborate with academia and vendors on novel technologies; Establish project strategy and guide team execution; Direct supervision and mentorship of 3-5 scientists
Seniority
Principal, strategic leadership with direct supervision
