Principal Scientist, Biocatalysis
Core
Lead the development of enzymes and biocatalytic processes for small-molecule synthesis while implementing digital tools and laboratory automation to accelerate enzyme engineering.
Role type
Principal Scientist, Biocatalysis (Strategy & Hands-on IC)
Builds
Biocatalysts with novel functions for efficient and sustainable manufacturing processes
Domain
Biopharmaceuticals / Biocatalysis / Process R&D
Deliverable
production ML models | product features | infrastructure
Required skills
Biocatalytic process development, Enzyme engineering (directed evolution), Laboratory automation (high-throughput), Python, SQL, Data science, Protein engineering
Preferred skills
Machine learning for protein engineering, Biochemical characterization, Drug development (CMC), Informatics integration
Technologies
Benchling, Biomek, Firefly, Dragonfly, Mantis
Responsibilities
Apply expertise in data science and automation to solve complex biocatalysis challenges; Lead development of digital tools for data ingestion, standardization, and analysis; Drive AI/ML and LLM-based approaches for experimental design; Lead design and scaling of high-throughput automation for enzyme engineering; Provide technical leadership, mentor scientists, and evaluate emerging technologies.
Seniority
Principal, strategic leadership with hands-on technical execution
