Senior Principal Scientist, Upstream Process Development Group Lead
Core
Lead upstream bioprocess development and scale-up for biologics, driving innovation in cell-culture processes and next-generation biomanufacturing technologies.
Role type
Senior Principal Scientist, Upstream Process Development Group Lead
Builds
Robust, scalable upstream processes and novel biomanufacturing technologies for biologics pipeline
Domain
Biopharmaceuticals / Bioprocessing
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Upstream bioprocessing, cell-culture process development, bioreactor scale-up, CMC development, cross-functional team leadership, regulatory filings, process characterization, scientific strategy
Preferred skills
Continuous biomanufacturing, perfusion process development, media/feed development, high-throughput experimentation, process modeling (omics/metabolic flux), microbial fermentation
Technologies
Bioreactors, Bioprocess Engineering, Cell Culture Techniques, Chemistry, Protein Characterization, Process Development (PD), Technology Development
Responsibilities
Shape and drive innovation across the Biologics pipeline; lead development of robust upstream processes for various clinical stages; improve process efficiency and cost-effectiveness; collaborate with academia and vendors on novel technologies; direct supervision and mentorship of 3-5 scientists; represent the group as an upstream bioprocess expert
Seniority
Principal, strategic leadership with direct supervision
