Senior Principal Scientist, Pharmacokinetics
Core
Provide scientific leadership for drug conjugate discovery and development, overseeing DMPK strategy and portfolio decisions from early discovery through clinical candidate nomination.
Role type
Senior Principal Scientist (Scientific Leadership & Team Management)
Builds
Drug conjugate and novel modality development programs
Domain
Pharmaceutical R&D, Drug Conjugates, DMPK
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
DMPK strategy, ADME experimentation, portfolio management, cross-functional team leadership, regulatory submission authoring, in vitro/in vivo data integration, nonclinical-to-clinical translation
Preferred skills
Antibody Drug Conjugates (ADC) discovery, model-informed drug discovery (PBPK, population PK), external scientific visibility
Technologies
None explicitly listed beyond general scientific domains
Responsibilities
Lead DMPK strategy for drug conjugates; Represent DMPK on cross-functional teams; Develop DMPK screening funnels and translational plans; Oversee LM ADME experimentation strategy; Contribute to portfolio management; Author regulatory and scientific documents; Manage and develop a team of investigators and experts; Monitor external scientific advances; Collaborate with internal teams and external partners
Seniority
Principal, strategy & mentorship
