Principal Scientist, Nonclinical Drug Safety Program Discovery
Core
Lead nonclinical drug safety strategy for discovery programs in immunology and oncology, assessing risks from target identification through First-In-Human studies.
Role type
Principal Scientist, Nonclinical Drug Safety Program Discovery
Builds
Novel medicines for patients via discovery research teams
Domain
Pharmaceutical industry, Drug Discovery, Immunology, Oncology
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Risk assessment, De-risking strategies, GLP toxicity study strategy, Cross-functional collaboration, Therapeutic target selection, Regulatory document safety sections
Preferred skills
Immunology background, Biopharmaceutical development, Small molecule development, Regulatory submissions
Technologies
GLP toxicology studies, Target identification, Lead optimization
Responsibilities
Represent NDS on discovery teams and participate in governance reviews, Promote creative thinking from target identification to lead optimization, Identify and assess potential risks associated with therapeutic targets, Lead early development teams informing preclinical studies, Define and oversee NDS strategy for programs in all modalities
Seniority
Principal, hands-on IC with strategic oversight
