Pioneering Medicines: Senior /Executive Director, Head of Toxicology
Core
Lead and build the toxicology function to define and execute nonclinical safety strategies across a diverse portfolio of therapeutic modalities, ensuring regulatory readiness from discovery through early clinical development.
Role type
Senior/Executive Director, Head of Toxicology
Builds
Nonclinical safety strategies, risk assessments, and IND/CTA-enabling plans for novel treatment options
Domain
Biopharmaceuticals / Drug Development
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Nonclinical safety strategy, GLP and non-GLP study oversight, risk assessment, IND/CTA planning, cross-functional partnership, team building and scaling, operating model design
Preferred skills
Experience with diverse therapeutic modalities, strategic alliance management
Technologies
GLP study protocols, IND/CTA regulatory frameworks
Responsibilities
Lead, build, and scale the toxicology function including internal team development and external partnerships; Define fit-for-purpose operating models spanning investigative and regulatory toxicology; Serve as the primary internal expert for nonclinical safety; Define and drive toxicology strategies across multiple programs and modalities; Translate findings into clear risk assessments, mitigation strategies, and IND/CTA-enabling plans; Oversee the design, execution, and interpretation of non-GLP and GLP toxicology studies; Partner cross-functionally to integrate safety into development strategy